LABORATORY CELL CULTURE BIOREACTOR

Fermenter/fermentation tank/fermentor/bioreactor

 Shanghai RITAI introduces a new generation of microcarrier Cell Culture Bioreactors. We adopt centrifugal lifting type Agitator, which has features of low shearing force, rapid solution circulation , shorter mixing time, and ability of linear scale up. And we adopt new type of aeration tube, which has features of foam free deep aeration, oxygen Transfer Rate (Kla between 4-8) satisfy.. Moreover, we also adopt unique decanting column, which has features of Simple structure, stable and reliable, Perfusion rate higher than 5 times of the working volume/per day, a self cleaning function and of features of liquid level being automatically controlled

ApplicationIt suit for mammalian animal cell culture. it is also available for suspension culture , anchorage independent and anchorage dependent cell line. Continuous perfusion is applicable, it can increase cell density, improve the health pattern of cell, and greatly increase cell product.

Model	CELLIPOWER08 SYSTEM
Working volume	5L,10L,15L
Filling volume	65-80%
Material	Special type of magnetic silicone glass , which can resist temp. and pressure. Wetted parts are SS316L, and others is SS304.
Stainless steel part finish	inside surface is 0.28-0.6μm by mechanical polishing, ( passivation or electropolish are optional) outside surface is 0.4-0.8μm by satin finish.
Pressure	ATM (atmospheric pressure)
Agitation	11. Fermentor use servo motor 2.top mechanical agitator , single mechanical seal 3.speed range:50-200rpm 4. Centrifugal lifting type agitator
Equips of vessel	1.using alcohol flame inoculation 2.electrical heater 3.PH,DO, temp. sensor foam and level probe port, etc.
construction	bench-top One fermentor vessel with one control system (simens PLC and HMI)
Operating panel	Chinese and English version
Main components and controls of system
PH	1.On-line check and measure, and digitization fully automatic control; 2.PH, CO2 and base gang control. Mass flow meter automatically adjusting CO2, peristaltic pump automatically adjusting base. 3.Control range 2-12pH, measure precision±0.01 pH, control precision±0.1 pH; 4. It has auto alarm function. 5.pH sensor and signal transmission line, mettler Toledo
DO	1.On-line check and measure; digital display. 2.Range 0-200%, precision ±1%; 3.It has auto alarm function; 4.DO sensor and signal transmission line, mettler Toledo
Feed controlperfusion	1.Automatically control and automatically alarm; 2.peristaltic pump automatically feeding and perfusion
Temp. control	1.PID fully digitization signal processing, digitization control settings 2.Measure range 0-150°C, control range 15-45°C,control precision±0.2°C 3.Pt 100Ωtemp. Sensor 4.system with electrical heater to control the temp inside vessel
Rotate speed	1.Automatically control , with auto alarm function 2.servo frequency converter to adjust the speed.
Air flow	Automatically adjusting with massflow meter
sterilization	Should sent to autoclave for sterilization
Control	Siemens PLC, and Siemens 10.4” LCD touch screen(HMI) and RITAI program
PC	1.PC with kingview software for recording function (optional) 2.PC with simens remote control and kingview recording function (optional) 3.printer (optional)

LABORATORY CELL CULTURE BIOREACTOR